Semiparametric variance components models for genetic studies with longitudinal phenotypes
نویسندگان
چکیده
منابع مشابه
Semiparametric variance components models for genetic studies with longitudinal phenotypes.
In a family-based genetic study such as the Framingham Heart Study (FHS), longitudinal trait measurements are recorded on subjects collected from families. Observations on subjects from the same family are correlated due to shared genetic composition or environmental factors such as diet. The data have a 3-level structure with measurements nested in subjects and subjects nested in families. We ...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2012
ISSN: 1468-4357,1465-4644
DOI: 10.1093/biostatistics/kxr027